modACDC - Association of Covariance for Detecting Differential
Co-Expression
A series of functions to implement association of
covariance for detecting differential co-expression (ACDC), a
novel approach for detection of differential co-expression that
simultaneously accommodates multiple phenotypes or exposures
with binary, ordinal, or continuous data types. Users can use
the default method which identifies modules by Partition or may
supply their own modules. Also included are functions to choose
an information loss criterion (ILC) for Partition using
OmicS-data-based Complex trait Analysis (OSCA) and Genome-wide
Complex trait Analysis (GCTA). The manuscript describing these
methods is as follows: Queen K, Nguyen MN, Gilliland F, Chun S,
Raby BA, Millstein J. "ACDC: a general approach for detecting
phenotype or exposure associated co-expression" (2023)
<doi:10.3389/fmed.2023.1118824>.